Warden Krieg in the Hidden Laboratory near the end of Act I is by far the best boss to farm at lower levels, because you get plenty of potential aetherial hero spawns along the way to fighting him.
The best spots to find plenty of these are types of enemies are The Hidden Laboratory (Act I), the Gates Of Necropolis (Act IV), Port Valbury (the roguelike challenge dungeon in Act III) and any area in the city of Malmouth (Ashes Of Malmouth expansion).
Nemesis spawns: These rare, high level atherials and aether corruptions won't spawn until you hit the lowest reputation with those factions, which won't happen until much later on a 2nd - 3rd playthrough on a higher difficulty. Bosses: Such as Commander Lucius, Warden Krieg, Herald Of The Flame, or The Amalgamation. Heroic creatures: These aetherials and aether corruptions are marked with the star next to their name and typically have extra titles such as Azar The Wrathful, Aetheron The Plaguebearer, or Kamladris the Rimeheart. Tainted Brain Matter will drop randomly from these creature types: Instead on relying on chests to effectively farm Tainted Brain Matter, your best bet is to go anywhere where aetherials and aether corruption creatures spawn at a high level. The locked chests that have to be opened with dynamite in Deadman's Gulch also occasionally drop them.įrankly, the percentage chance on chests is low enough that its more of a "Hey, cool, it finally dropped," than anything that can be reliably farmed, however, so this isn't the best way to go about finding rare crafting ingredients. 
In particular, I've had success finding Tainted Brain Matter after defeating The Master Of Flesh and opening the chests labeled as The Master's Trove at the end of Ashes of Malmouth.
Farming specific aetherials and aether corruptionsĪll of the rare crafting materials such as Tainted Brain Matter, Blood Of Ch'thon, and Ancient Hearts (very) occasionally drop from heroic chests, end boss chests, and one shot chests. There are three main ways to acquire Tainted Brain Matter, which we'll cover in depth below: Or the one where the electric touch of Louis’ soulmate isn’t enough to discount that he's a bit of a dickhead.Tainted Brain Matter is one rare material that players have trouble finding, especially as they level up and outpace the starting normal mode difficulty. Prince Harry Styles reluctantly leaves London for yet another diplomatic visit, this time to the tiny island of Tristan da Cunha. Allwaswell16 Fandoms: One Direction (Band)Īlthough Louis Tomlinson lived most of his life on the most remote island in the world, now he’s ready to leave home, attend university, and maybe have a chance at finding his soulmate.
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